Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.58 |
| ▸ | PPARA | Q07869 | 2/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 7/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467443 | 0.81 | NR4A2 (0.50) | NR4A2MRGPRX4GPBAR1CYSLTR1NPC1 | |
| SCHEMBL7470170 | 0.80 | NR4A2 (0.56) | PPARDNR4A2MRGPRX4GPBAR1CYSLTR1 | |
| SCHEMBL7473175 | 0.79 | NR4A2 (0.48) | NR4A2MRGPRX4GPBAR1CYSLTR1NPC1 | |
| SCHEMBL7472699 | 0.79 | NR4A2 (0.48) | NR4A2MRGPRX4GPBAR1CYSLTR1NPC1 | |
| SCHEMBL9721952 | 0.79 | NR4A2 (0.61) | PPARANR4A2MRGPRX4GPBAR1CYSLTR1 | |
| Benzoic Acid SCHEMBL2284793 | 0.79 | RAB9A (0.53) | NR1H4MAPTNPC1RAB9ATDP1 | |
| SCHEMBL7471030 | 0.78 | NR4A2 (0.47) | NR4A2MRGPRX4GPBAR1CYSLTR1NPC1 | |
| SCHEMBL3569948 | 0.78 | MRGPRX4 (0.52) | PPARDPPARANR4A2MRGPRX4MAPT | |
| SCHEMBL14236726 | 0.77 | MAPT (0.52) | PPARDPPARAMAPTNPC1RAB9A | |
| SCHEMBL13484535 | 0.75 | PPARD (0.96) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786457-B1 | AZOLE DERIVATIVES | YAMANOUCHI PHARMA CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5981559-A | USEFUL IN PREVENTING OR TREATING ALLERGIC DISEASES, ISCHEMIC HEART DISEASES OR ISCHEMIC BRAIN DISEASES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0786457-A1 | AZOLE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |