Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 10/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.44 |
| ▸ | CPT2 | P23786 | 1/20 | 0.43 |
| ▸ | CPT1A | P50416 | 1/20 | 0.43 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473175 | 0.95 | NR4A2 (0.48) | NR4A2MRGPRX4GPBAR1CYSLTR1NPC1 | |
| SCHEMBL7472699 | 0.95 | NR4A2 (0.48) | NR4A2MRGPRX4GPBAR1CYSLTR1NPC1 | |
| SCHEMBL7471030 | 0.94 | NR4A2 (0.47) | NR4A2MRGPRX4GPBAR1CYSLTR1NPC1 | |
| SCHEMBL7478013 | 0.81 | PPARD (0.58) | NR4A2MRGPRX4GPBAR1CYSLTR1NPC1 | |
| SCHEMBL5708664 | 0.80 | MAOA (0.48) | NPC1RAB9A | |
| SCHEMBL7470170 | 0.78 | NR4A2 (0.56) | NR4A2MRGPRX4GPBAR1CYSLTR1NPC1 | |
| SCHEMBL5708655 | 0.77 | MAOA (0.47) | NPC1RAB9AKMT2A | |
| SCHEMBL7477308 | 0.74 | GRM2 (0.43) | MRGPRX4CPT2CPT1ACPT1B | |
| SCHEMBL9721952 | 0.72 | NR4A2 (0.61) | NR4A2MRGPRX4GPBAR1CYSLTR1NPC1 | |
| SCHEMBL7475391 | 0.70 | NR4A2 (0.50) | NR4A2MRGPRX4GPBAR1CYSLTR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786457-B1 | AZOLE DERIVATIVES | YAMANOUCHI PHARMA CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5981559-A | USEFUL IN PREVENTING OR TREATING ALLERGIC DISEASES, ISCHEMIC HEART DISEASES OR ISCHEMIC BRAIN DISEASES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0786457-A1 | AZOLE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |