Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | FABP6 | P51161 | 1/20 | 0.40 |
| ▸ | F9 | P00740 | 3/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23522705 | 0.85 | PRKAG1 (0.56) | F10CACNA1GEGLN1PDE10ALMNA | |
| SCHEMBL4244757 | 0.79 | TDP1 (0.39) | MEN1MAPTKMT2ATDP1HSD17B10 | |
| SCHEMBL3011310 | 0.76 | KMT2A (0.66) | MEN1MAPTKMT2AATMTDP1 | |
| SCHEMBL16186535 | 0.75 | CACNA1G (0.56) | MEN1MAPTKMT2AATMTDP1 | |
| Hydrochloric Acid SCHEMBL30103090 | 0.75 | HDAC3 (0.44) | MAPTTDP1PSMD14MMP2EGLN1 | |
| SCHEMBL31735460 | 0.75 | MEN1 (0.60) | MEN1MAPTKMT2AATMTDP1 | |
| SCHEMBL5897142 | 0.73 | KMT2A (0.57) | MEN1MAPTKMT2AATMTDP1 | |
| SCHEMBL10885693 | 0.72 | MEN1 (0.60) | MEN1MAPTKMT2AATMTDP1 | |
| SCHEMBL1507294 | 0.72 | ALDH1A1 (0.35) | MEN1MAPTKMT2ATDP1LMNA | |
| SCHEMBL11222676 | 0.71 | KMT2A (0.68) | MEN1MAPTKMT2AATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171435-A2 | PYRIMIDINE-2-ONE DERIVATIVES AS INTEGRIN RECEPTOR LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000061551-A2 | PYRIMIDINE-2-ONE DERIVATIVES AS INTEGRIN RECEPTOR LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-19 | — | — | WO | disclosed |