Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479313 | 0.89 | HRH3 (0.31) | HRH3 | |
| SCHEMBL7477219 | 0.88 | SCN9A (0.31) | SCN9A | |
| SCHEMBL7416015 | 0.85 | KMT2A (0.34) | HRH3 | |
| SCHEMBL7411562 | 0.84 | KMT2A (0.35) | HRH3 | |
| SCHEMBL7411225 | 0.84 | KMT2A (0.35) | HRH3 | |
| SCHEMBL7478780 | 0.83 | HRH3 (0.32) | HRH3 | |
| SCHEMBL7405119 | 0.82 | — | — | |
| SCHEMBL8506871 | 0.82 | ALDH1A1 (0.37) | — | |
| SCHEMBL8506868 | 0.82 | ALDH1A1 (0.37) | — | |
| SCHEMBL7412567 | 0.80 | HRH3 (0.36) | SCN9AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950057-B1 | 3-PYRIDYL ENANTIOMERS AND THEIR USE AS ANALGESICS | ABBOTT LAB (US) | 2002-11-13 | — | — | EP | disclosed |
| US-6403575-B1 | ANTI-INFLAMMATORIES | ABBOTT LABORATORIES | 2002-06-11 | — | — | US | disclosed |
| US-6133253-A | NEURONAL CELL DEATH PREVENTORS AND ANTI-INFLAMMATORIES | ABBOTT LABORATORIES (US) | 2000-10-17 | — | — | US | disclosed |
| EP-0950057-A1 | 3-PYRIDYL ENANTIOMERS AND THEIR USE AS ANALGESICS | Abbott Laboratories (US) | 1999-10-20 | — | — | EP | disclosed |
| WO-1998025920-A1 | 3-PYRIDYL ENANTIOMERS AND THEIR USE AS ANALGESICS | ABBOTT LABORATORIES (US) | 1998-06-18 | — | — | WO | disclosed |