Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MIF | P14174 | 16/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CALML3 | P27482 | 1/20 | 0.36 |
| ▸ | SDHA | P31040 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473717 | 0.91 | MIF (0.48) | RAB9AMIFMAOAMAOBLMNA | |
| SCHEMBL7474027 | 0.86 | MAOA (0.48) | RAB9AMIFNPC1SMN1; SMN2MAOA | |
| SCHEMBL7477204 | 0.82 | MIF (0.54) | RAB9AMIFNPC1SMN1; SMN2 | |
| SCHEMBL7471632 | 0.82 | MIF (0.47) | RAB9AMIFNPC1SMN1; SMN2 | |
| SCHEMBL5655616 | 0.80 | MIF (0.38) | RAB9AMIFMAOA | |
| SCHEMBL5656862 | 0.80 | MIF (0.38) | RAB9AMIFMAOA | |
| SCHEMBL7463009 | 0.80 | MIF (0.53) | RAB9AMIFMAOAMAOBLMNA | |
| SCHEMBL7468825 | 0.78 | MAOB (0.59) | RAB9AMIFNPC1MAOAMAOB | |
| SCHEMBL14345346 | 0.78 | MAOB (0.59) | RAB9AMIFNPC1MAOAMAOB | |
| SCHEMBL7471239 | 0.78 | MIF (0.50) | RAB9AMIFMAOAMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054874-B1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | UPJOHN CO (US) | 2002-08-28 | — | — | EP | claimed |