Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7475937 | 0.99 | MEN1 (0.47) | MEN1KMT2APDE4BHCRTR2THRB | |
| SCHEMBL7477389 | 0.94 | KMT2A (0.53) | MEN1KMT2APDE4BHCRTR2THRB | |
| SCHEMBL7475137 | 0.94 | KMT2A (0.53) | MEN1KMT2APDE4BHCRTR2THRB | |
| SCHEMBL7479310 | 0.84 | ACHE (0.43) | KDM4EBCHEACHENPSR1 | |
| Hydrochloric Acid SCHEMBL7479308 | 0.84 | ACHE (0.43) | KDM4EBCHEACHE | |
| SCHEMBL7483483 | 0.83 | DRD3 (0.48) | MEN1KMT2APDE4BHCRTR2KDM4E | |
| SCHEMBL7484532 | 0.82 | KMT2A (0.42) | MEN1KMT2APDE4BHCRTR2THRB | |
| SCHEMBL7487783 | 0.82 | KMT2A (0.53) | MEN1KMT2APDE4BHCRTR2THRB | |
| Hydrochloric Acid SCHEMBL7482671 | 0.82 | DRD3 (0.47) | MEN1KMT2APDE4BHCRTR2KDM4E | |
| Hydrochloric Acid SCHEMBL7490610 | 0.81 | KMT2A (0.52) | MEN1KMT2APDE4BHCRTR2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950056-B1 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |
| EP-0950056-B1 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | disclosed |