Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7479308 | 0.99 | ACHE (0.43) | ACHEPTGESKDM4EBCHERAB9A | |
| SCHEMBL7484036 | 0.94 | ACHE (0.43) | ACHEBCHERAB9ANPSR1 | |
| SCHEMBL7477425 | 0.89 | ACHE (0.46) | ACHEBCHERAB9ANPSR1 | |
| SCHEMBL7478479 | 0.84 | MEN1 (0.48) | ACHEKDM4EBCHENPSR1 | |
| Hydrochloric Acid SCHEMBL7475937 | 0.84 | MEN1 (0.47) | ACHEKDM4EBCHE | |
| SCHEMBL7477503 | 0.82 | DRD1 (0.52) | — | |
| SCHEMBL7475137 | 0.78 | KMT2A (0.53) | ACHEKDM4EBCHENPSR1 | |
| SCHEMBL7477389 | 0.78 | KMT2A (0.53) | ACHEKDM4EBCHENPSR1 | |
| SCHEMBL7484532 | 0.77 | KMT2A (0.42) | ACHEKDM4EBCHENPSR1 | |
| SCHEMBL7483332 | 0.76 | DRD1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950056-B1 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |