Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472452 | 0.91 | THRB (0.39) | THRBHSD17B10MAPK1ALOX15HTT | |
| SCHEMBL7159785 | 0.91 | ITGB3 (0.42) | THRBHSD17B10MAPK1ALOX15HTT | |
| SCHEMBL7369546 | 0.89 | THRB (0.39) | THRBHSD17B10MAPK1ALOX15HTT | |
| SCHEMBL7371562 | 0.89 | THRB (0.39) | THRBHSD17B10MAPK1ALOX15HTT | |
| SCHEMBL7365336 | 0.87 | TSHR (0.43) | THRBHSD17B10MAPK1ALOX15HTT | |
| SCHEMBL7366599 | 0.87 | ITGB3 (0.41) | THRBHSD17B10MAPK1ALOX15HTT | |
| SCHEMBL4685454 | 0.86 | ITGB3 (0.36) | THRBHSD17B10ALOX15L3MBTL1TSHR | |
| SCHEMBL7368383 | 0.86 | GAA (0.37) | THRBHSD17B10MAPK1ALOX15HTT | |
| SCHEMBL7468966 | 0.85 | BDKRB1 (0.39) | THRBHSD17B10MAPK1HTTTSHR | |
| SCHEMBL7165010 | 0.84 | ITGB3 (0.41) | THRBHSD17B10MAPK1ALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964856-B1 | BICYCLIC AMINO ACIDS | MERCK PATENT GMBH (DE) | 2002-10-09 | — | — | EP | disclosed |