Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575462 | 0.95 | CRHR1 (0.32) | CRHR1TSHRTDP1USP2ALOX15 | |
| SCHEMBL13297994 | 0.95 | CRHR1 (0.32) | CRHR1TSHRTDP1USP2ALOX15 | |
| SCHEMBL3141109 | 0.93 | CRHR1 (0.34) | CRHR1 | |
| SCHEMBL1138674 | 0.93 | ALOX15 (0.31) | ALOX15 | |
| SCHEMBL11429391 | 0.92 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL9497027 | 0.92 | MAPT (0.36) | CRHR1 | |
| SCHEMBL10000503 | 0.90 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL10325634 | 0.90 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL14256358 | 0.90 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL11436419 | 0.90 | CRHR1 (0.33) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227640-B1 | POLYOLEFINS STABILISED BY BIS-(POLYALKYLPIPERIDINYL-AMINO)-1,3,5-TRIAZINES | CIBA-GEIGY AG (CH) | 1993-05-26 | — | — | EP | claimed |
| EP-0309402-B2 | N-substituted hindered amine stabilizers | CIBA SC HOLDING AG (CH) | 2002-06-12 | — | — | EP | disclosed |
| EP-0309402-B1 | N-substituted hindered amine stabilizers | CIBA GEIGY AG (CH) | 1995-01-11 | — | — | EP | disclosed |
| EP-0227640-B1 | POLYOLEFINS STABILISED BY BIS-(POLYALKYLPIPERIDINYL-AMINO)-1,3,5-TRIAZINES | CIBA-GEIGY AG (CH) | 1993-05-26 | — | — | EP | disclosed |
| US-5204473-A | O-substituted N-hydroxy hindered amine stabilizers | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0309402-A1 | N-substituted hindered amine stabilizers | CIBA-GEIGY AG (CH) | 1989-03-29 | — | — | EP | disclosed |