SCHEMBL3141109

SCHEMBL3141109

CCCCN(CCCC)c1nc(N(CCCC)C2CC(C)(C)NC(C)(C)C2)nc(N(CCCC)C2CC(C)(C)NC(C)(C)C2)n1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 3/20 0.34
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14256358 0.97 CRHR1 (0.33) CRHR1
SCHEMBL10000503 0.97 CRHR1 (0.33) CRHR1
SCHEMBL10325634 0.97 CRHR1 (0.33) CRHR1
SCHEMBL16253396 0.96 CRHR1 (0.32) CRHR1
SCHEMBL9575336 0.96 CRHR1 (0.32) CRHR1
SCHEMBL13297996 0.96 CRHR1 (0.32) CRHR1
SCHEMBL9497027 0.96 MAPT (0.36) CRHR1MAPTSMN1; SMN2
SCHEMBL1138674 0.94 ALOX15 (0.31)
SCHEMBL9575304 0.93 CRHR1 (0.36) CRHR1MAPTSMN1; SMN2
SCHEMBL7478540 0.93 CRHR1 (0.36) CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0227640-B1 POLYOLEFINS STABILISED BY BIS-(POLYALKYLPIPERIDINYL-AMINO)-1,3,5-TRIAZINES CIBA-GEIGY AG (CH) 1993-05-26 EP claimed
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION MITSUI CHEMICALS, INC. (JP) 2010-03-25 US disclosed
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION MITSUI CHEMICALS, INC. (JP) 2010-03-25 US disclosed
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION MITSUI CHEMICALS, INC. (JP) 2010-03-25 US disclosed
EP-0227640-B1 POLYOLEFINS STABILISED BY BIS-(POLYALKYLPIPERIDINYL-AMINO)-1,3,5-TRIAZINES CIBA-GEIGY AG (CH) 1993-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION SEM1, WDR5, WDR1 CRHR1 2935/4885MAPT 348/4885SMN1; SMN2 2221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.