Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30666567 | 0.81 | CTSS (0.31) | CTSSCTSKSMN1; SMN2 | |
| SCHEMBL30666988 | 0.81 | TRPV3 (0.36) | CTSSCTSKSMN1; SMN2 | |
| Bromide SCHEMBL30666412 | 0.79 | CTSS (0.30) | CTSSCTSK | |
| SCHEMBL23581343 | 0.78 | CTSS (0.30) | CTSSCTSK | |
| SCHEMBL8275624 | 0.77 | CTSS (0.31) | CTSSCTSKSMN1; SMN2 | |
| SCHEMBL10598028 | 0.75 | ALDH1A1 (0.40) | — | |
| SCHEMBL2200088 | 0.74 | SMN1; SMN2 (0.35) | CTSSCTSKSMN1; SMN2 | |
| SCHEMBL1678475 | 0.73 | — | — | |
| SCHEMBL12033840 | 0.73 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL22183962 | 0.73 | PIK3CD (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937708-B1 | Sulphonamide derivatives | LILLY CO ELI (US) | 2002-12-18 | — | — | EP | disclosed |
| US-6362230-B1 | ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6174922-B1 | FOR POTENTIATING GLUTAMATE RECEPTOR FUNCTION IN WARM BLOODED MAMMAL | ELI LILLY AND COMPANY | 2001-01-16 | — | — | US | disclosed |
| EP-0937708-A2 | sulphonamide derivatives | ELI LILLY AND COMPANY (US) | 1999-08-25 | — | — | EP | disclosed |