Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.50 |
| ▸ | RAB9A | P51151 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463048 | 0.82 | CYP3A4 (0.57) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL7470064 | 0.80 | CPB1 (0.48) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL7637970 | 0.79 | MEN1 (0.50) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL7532393 | 0.78 | RAB9A (0.47) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL7471959 | 0.77 | KMT2A (0.54) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL7470299 | 0.73 | MGLL (0.62) | MEN1KMT2ARAB9ANPC1MAPT | |
| Hydrochloric Acid SCHEMBL7470042 | 0.72 | MGLL (0.61) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL14825155 | 0.72 | RAB9A (0.75) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL7463271 | 0.72 | RAB9A (0.60) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL27511900 | 0.72 | MEN1 (0.56) | MEN1KMT2ARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871619-B1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMA (US) | 2002-11-06 | — | — | EP | disclosed |
| US-6057451-A | AMINOTHIAZOLE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-05-02 | — | — | US | disclosed |