Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | UNG | P13051 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478870 | 1.00 | NR1H4 (0.52) | NR1H4TTRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17336959 | 0.91 | KMO (0.51) | NR1H4TTRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17336957 | 0.91 | KMO (0.51) | NR1H4TTRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9514548 | 0.83 | ALOX5 (0.51) | NPC1RAB9ASMN1; SMN2KDM4EPARP1 | |
| SCHEMBL9514540 | 0.83 | ALOX5 (0.51) | NPC1RAB9ASMN1; SMN2KDM4EPARP1 | |
| SCHEMBL9514841 | 0.80 | CYP19A1 (0.54) | NPC1RAB9ASMN1; SMN2KDM4EPARP1 | |
| SCHEMBL5777558 | 0.80 | CYP19A1 (0.54) | NPC1RAB9ASMN1; SMN2KDM4EPARP1 | |
| SCHEMBL9514907 | 0.80 | ALB (0.48) | NR1H4NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7466164 | 0.79 | TTR (0.48) | TTRNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7466155 | 0.79 | TTR (0.48) | TTRNPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786457-B1 | AZOLE DERIVATIVES | YAMANOUCHI PHARMA CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5981559-A | USEFUL IN PREVENTING OR TREATING ALLERGIC DISEASES, ISCHEMIC HEART DISEASES OR ISCHEMIC BRAIN DISEASES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0786457-A1 | AZOLE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |