Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | ATP4A | P20648 | 2/20 | 0.43 |
| ▸ | ATP4B | P51164 | 2/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514540 | 1.00 | ALOX5 (0.51) | ALOX5HSD17B1HSD17B2LCKCYSLTR2 | |
| SCHEMBL9514841 | 0.83 | CYP19A1 (0.54) | KDM4EALDH1A1HPGDCYP19A1PARP1 | |
| SCHEMBL5777558 | 0.83 | CYP19A1 (0.54) | KDM4EALDH1A1HPGDCYP19A1PARP1 | |
| SCHEMBL7478874 | 0.83 | NR1H4 (0.52) | KDM4EALDH1A1PARP1MEN1NPC1 | |
| SCHEMBL7478870 | 0.83 | NR1H4 (0.52) | KDM4EALDH1A1PARP1MEN1NPC1 | |
| SCHEMBL19196288 | 0.81 | PARP1 (0.43) | KDM4EALDH1A1HPGDPARP1ADAMTS5 | |
| SCHEMBL9514907 | 0.78 | ALB (0.48) | KDM4EALDH1A1HPGDPARP1MEN1 | |
| SCHEMBL28479905 | 0.77 | MAPT (0.50) | KDM4EALDH1A1HPGDPARP1MEN1 | |
| SCHEMBL17336957 | 0.76 | KMO (0.51) | KDM4EALDH1A1PARP1MEN1NPC1 | |
| SCHEMBL17336959 | 0.76 | KMO (0.51) | KDM4EALDH1A1PARP1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219436-B1 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI CHEM IND (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4902700-A | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0219436-A2 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | disclosed |