Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 3/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | GPR6 | P46095 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7485053 | 0.95 | PTGES (0.33) | MAP3K7HDAC3BRD4HDAC4HDAC1 | |
| SCHEMBL7975620 | 0.93 | AVPR2 (0.34) | MAP3K7HDAC3BRD4HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL7953946 | 0.92 | AVPR2 (0.34) | MAP3K7HDAC3BRD4HDAC4HDAC1 | |
| SCHEMBL7963910 | 0.91 | PTK2 (0.33) | MAP3K7HDAC3BRD4HDAC4HDAC1 | |
| SCHEMBL7965063 | 0.91 | PTGES (0.34) | MAP3K7HDAC3BRD4HDAC4HDAC1 | |
| SCHEMBL7964770 | 0.91 | MAP3K7 (0.33) | MAP3K7HDAC3BRD4HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL7970313 | 0.90 | PTK2 (0.33) | MAP3K7HDAC3BRD4HDAC4HDAC1 | |
| SCHEMBL7966512 | 0.90 | BTK (0.34) | MAP3K7HDAC3BRD4HDAC4HDAC1 | |
| SCHEMBL7482003 | 0.90 | MAP3K7 (0.33) | MAP3K7HDAC3BRD4HDAC4HDAC1 | |
| SCHEMBL7967059 | 0.90 | JAK2 (0.33) | MAP3K7GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |