Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803374 | 0.78 | PPARG (0.45) | L3MBTL1PPARGCYP2C9TSHRTP53 | |
| SCHEMBL6802789 | 0.77 | CNR1 (0.47) | L3MBTL1PPARGCYP2C9TSHRHTT | |
| SCHEMBL6804905 | 0.76 | KDM4E (0.54) | PPARGCYP2C9TSHRKDM4EALDH1A1 | |
| SCHEMBL6808746 | 0.76 | ROCK2 (0.48) | L3MBTL1PPARGCYP2C9TSHRHTT | |
| SCHEMBL6799418 | 0.76 | PPARG (0.45) | L3MBTL1PPARGCYP2C9TSHRHTT | |
| SCHEMBL6628576 | 0.76 | CYP2C9 (0.56) | PPARGCYP2C9TSHRTP53HTT | |
| SCHEMBL6804264 | 0.75 | NR2E1 (0.52) | L3MBTL1PPARGCYP2C9TSHRNPC1 | |
| SCHEMBL7476515 | 0.75 | MAPT (0.49) | TP53MAPTNR2E3KDM4EALDH1A1 | |
| SCHEMBL678882 | 0.73 | ALDH1A1 (0.59) | PPARGCYP2C9TSHRHTTALDH1A1 | |
| SCHEMBL6759795 | 0.72 | CYP2C9 (0.50) | L3MBTL1PPARGCYP2C9TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216240-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001025229-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-12 | — | — | WO | disclosed |