Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 9/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | LDLR | P01130 | 3/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 3/20 | 0.44 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.44 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803481 | 0.83 | PPARG (0.42) | PPARGCYP2C9TSHRDRD2DRD4 | |
| SCHEMBL6757844 | 0.82 | PPARG (0.41) | PPARGCYP2C9TSHRDRD2DRD4 | |
| SCHEMBL6628576 | 0.76 | CYP2C9 (0.56) | PPARGCYP2C9TSHRDRD2DRD4 | |
| SCHEMBL6808666 | 0.76 | NR2E1 (0.56) | NR2E1MAPK13LDLRPCSK9KIT | |
| SCHEMBL7479042 | 0.75 | L3MBTL1 (0.44) | PPARGCYP2C9TSHRL3MBTL1NPC1 | |
| SCHEMBL6756601 | 0.75 | HSP90AA1 (0.38) | NR2E1PPARGCYP2C9TSHRDRD2 | |
| SCHEMBL31285175 | 0.74 | ABL1 (0.45) | PPARGCYP2C9TSHRABL1DRD2 | |
| SCHEMBL678882 | 0.74 | ALDH1A1 (0.59) | PPARGCYP2C9TSHRNPC1RAB9A | |
| SCHEMBL6757729 | 0.74 | KDM4E (0.41) | TSHRNPC1RAB9A | |
| SCHEMBL6754382 | 0.73 | PPARG (0.48) | PPARGCYP2C9TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040266774-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-30 | — | — | US | disclosed |
| US-6770667-B1 | N-((IMIDAZOLYL)-PHENYL)-FLUORENE-1-CARBOXAMIDE DERIVATIVES; 5-HYDROXYTRYPTAMINE (5-HT) ANTAGONISTS; PSYCHOLOGICAL, NERVOUS SYSTEM, EATING, BRAIN AND SLEEP DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266774-A1 | Amide compounds | TPH1, HTR1A, HTR5A | NR2E1 1288/4885MAPK13 4003/4885LDLR 3759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.