Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 16/20 | 0.43 |
| ▸ | MMP1 | P03956 | 8/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358396 | 0.84 | MMP3 (0.43) | MMP3MMP1CA1CA2MMP2 | |
| SCHEMBL7358596 | 0.79 | MMP3 (0.46) | MMP3MMP1CA1CA2MMP2 | |
| SCHEMBL7398436 | 0.72 | MMP1 (0.45) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL7365474 | 0.70 | MMP3 (0.42) | MMP3MMP1CA1CA2MMP2 | |
| SCHEMBL7359112 | 0.69 | MMP3 (0.42) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL7475200 | 0.68 | MMP3 (0.47) | MMP3MMP1CA1CA2MMP2 | |
| SCHEMBL6968692 | 0.67 | MMP3 (0.56) | MMP3MMP1CA2MMP2MMP9 | |
| SCHEMBL6968687 | 0.67 | MMP3 (0.56) | MMP3MMP1CA2MMP2MMP9 | |
| SCHEMBL8705613 | 0.67 | MMP3 (0.51) | MMP3MMP1CA1CA2MMP2 | |
| SCHEMBL8708490 | 0.66 | MMP3 (0.52) | MMP3MMP1CA1CA2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |
| US-5677282-A | ENZYME INHIBITOR; OSTEOARTHRITIS AND RHEUMATIC DISORDERS | PROSCRIPT, INC. (US) | 1997-10-14 | — | — | US | disclosed |