Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479396 | 1.00 | SLC6A9 (0.33) | SLC6A9SLC10A2NQO2MTNR1AMTNR1B | |
| SCHEMBL8206173 | 0.93 | SLC10A2 (0.35) | SLC6A9SLC10A2 | |
| SCHEMBL7484166 | 0.88 | MEN1 (0.38) | SLC10A2MEN1KMT2A | |
| SCHEMBL7484164 | 0.88 | MEN1 (0.38) | SLC10A2MEN1KMT2A | |
| SCHEMBL7478280 | 0.86 | SLC10A2 (0.35) | SLC10A2NQO2MTNR1AMTNR1B | |
| SCHEMBL7478273 | 0.86 | SLC10A2 (0.35) | SLC10A2NQO2MTNR1AMTNR1B | |
| SCHEMBL8693323 | 0.84 | SLC10A2 (0.37) | SLC10A2 | |
| SCHEMBL8798027 | 0.84 | SLC10A2 (0.37) | SLC10A2 | |
| SCHEMBL8693241 | 0.82 | SLC6A9 (0.36) | SLC6A9SLC10A2NQO2MTNR1AMTNR1B | |
| SCHEMBL8798356 | 0.82 | SLC6A9 (0.36) | SLC6A9SLC10A2NQO2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683774-B1 | HYPOLIPIDAEMIC COMPOUNDS | WELLCOME FOUND (GB) | 2002-10-09 | — | — | EP | disclosed |
| US-5723458-A | 1,4-BENZOTHIAZEPINES | GLAXO WELLCOME INC. (US) | 1998-03-03 | — | — | US | disclosed |
| WO-1994018184-A1 | HYPOLIPIDAEMIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-08-18 | — | — | WO | disclosed |