Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478797 | 0.80 | POLB (0.40) | — | |
| SCHEMBL3466455 | 0.77 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL21798314 | 0.75 | MEN1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL5498553 | 0.75 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL7315311 | 0.74 | MAPT (0.43) | ALDH1A1 | |
| SCHEMBL12144393 | 0.71 | CA1 (0.33) | — | |
| SCHEMBL10138961 | 0.68 | LMNA (0.35) | ALDH1A1 | |
| SCHEMBL18135520 | 0.67 | — | — | |
| SCHEMBL12605123 | 0.65 | NPC1 (0.30) | ALDH1A1 | |
| SCHEMBL12142677 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975594-B1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES | PFIZER LTD (GB) | 2002-09-18 | — | — | EP | disclosed |
| US-6281357-B1 | HEADACHE THERAPY | PFIZER INC | 2001-08-28 | — | — | US | disclosed |
| EP-0975594-A1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES | Pfizer Limited (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1999002493-A1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES | PFIZER LIMITED (GB) | 1999-01-21 | — | — | WO | disclosed |