Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CRHBP | P24387 | 1/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.61 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13500566 | 0.98 | HCAR3 (0.64) | HCAR3MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7180261 | 0.87 | HCAR3 (0.60) | HCAR3MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7180257 | 0.87 | HCAR3 (0.60) | HCAR3MAPTALDH1A1LMNASMN1; SMN2 | |
| Bromide SCHEMBL11023029 | 0.86 | HCAR3 (0.52) | HCAR3MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7981300 | 0.82 | HCAR3 (0.63) | HCAR3MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL23786250 | 0.82 | MAPT (0.69) | HCAR3MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8607686 | 0.82 | MAPT (0.69) | HCAR3MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17048217 | 0.82 | HCAR3 (0.66) | HCAR3MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6562168 | 0.82 | HCAR3 (0.66) | HCAR3MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3950396 | 0.82 | HCAR3 (0.57) | HCAR3MAPTALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |
| EP-1071669-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054313-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |