Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 8/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941298 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPTTSHRMAPK1MEN1 | |
| SCHEMBL11820042 | 0.74 | KMT2A (0.45) | ALDH1A1MAPTTSHRMAPK1MEN1 | |
| SCHEMBL15492070 | 0.72 | HPGD (0.48) | ALDH1A1MAPTTSHRMAPK1MEN1 | |
| SCHEMBL7654082 | 0.72 | MEN1 (0.56) | MAPTTSHRMAPK1MEN1KMT2A | |
| SCHEMBL21996116 | 0.71 | GRM5 (0.42) | ALDH1A1MAPTTSHRMAPK1MEN1 | |
| SCHEMBL11081773 | 0.71 | MAPT (0.58) | ALDH1A1MAPTTSHRMAPK1MEN1 | |
| SCHEMBL6940053 | 0.71 | CASP3 (0.58) | ALDH1A1HPGDLMNAGRM5RXFP1 | |
| SCHEMBL13007428 | 0.70 | MEN1 (0.46) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL6318770 | 0.70 | HDAC1 (0.58) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL13007386 | 0.69 | ALDH1A1 (0.50) | ALDH1A1MAPTTSHRMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080069-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999054284-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-28 | — | — | WO | disclosed |