Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177990 | 0.88 | FFAR4 (0.53) | FFAR4L3MBTL1ALDH1A1POLBMAPT | |
| SCHEMBL29387718 | 0.81 | FFAR4 (0.52) | FFAR4L3MBTL1ALDH1A1POLBMAPT | |
| SCHEMBL336755 | 0.81 | FFAR4 (0.52) | FFAR4L3MBTL1ALDH1A1POLBMAPT | |
| SCHEMBL6180609 | 0.80 | FFAR4 (0.50) | FFAR4L3MBTL1ALDH1A1POLBMAPT | |
| SCHEMBL7004883 | 0.71 | L3MBTL1 (0.56) | FFAR4L3MBTL1ALDH1A1POLBMAPT | |
| SCHEMBL8723629 | 0.71 | MAPT (0.52) | FFAR4L3MBTL1ALDH1A1POLBMAPT | |
| SCHEMBL6182443 | 0.70 | FFAR4 (0.48) | FFAR4L3MBTL1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL8723508 | 0.70 | GAA (0.58) | L3MBTL1ALDH1A1MAPTP2RY1GAA | |
| SCHEMBL8507695 | 0.70 | MAPT (0.56) | L3MBTL1ALDH1A1POLBMAPTP2RY1 | |
| SCHEMBL5838876 | 0.69 | CYP1A2 (0.48) | FFAR4L3MBTL1ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200414-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-02 | — | — | EP | disclosed |
| WO-2000063183-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIMIDINES | AMERICAN CYANAMID COMPANY (US) | 2000-10-26 | — | — | WO | disclosed |