Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.45 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.45 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.45 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.45 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478753 | 0.96 | EED (0.45) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL7477789 | 0.82 | PDE4D (0.43) | PDE4BPDE4DPDE4APDE4CGPR119 | |
| SCHEMBL7485838 | 0.82 | PDE4D (0.43) | PDE4BPDE4DPDE4APDE4CGPR119 | |
| SCHEMBL7475671 | 0.82 | CHEK2 (0.48) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL7475661 | 0.80 | CHEK2 (0.48) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL7486430 | 0.79 | CHEK2 (0.53) | PDE4BPDE4DPDE4APDE4CGPR119 | |
| SCHEMBL7475252 | 0.77 | KDM4E (0.38) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL7488290 | 0.77 | TBK1 (0.40) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL3157416 | 0.76 | PDE4B (0.52) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL5970662 | 0.75 | PDE4B (0.45) | EEDRBBP4SUZ12EZH2AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865281-B1 | NAPHTHYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICOAGULANTS | BERLEX LAB (US) | 2002-04-03 | — | — | EP | disclosed |
| US-5849759-A | Naphthyl-substituted benzimidazole derivatives as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1998-12-15 | — | — | US | disclosed |