Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.40 |
| ▸ | CCKAR | P32238 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920133 | 0.76 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL7069964 | 0.74 | FDFT1 (0.37) | CCKBRALDH1A1POLBTHRB | |
| SCHEMBL8548817 | 0.72 | CCKBR (0.38) | CCKBRCCKARALDH1A1 | |
| SCHEMBL8544961 | 0.66 | CCKBR (0.61) | CCKBRCCKAR | |
| SCHEMBL8546357 | 0.66 | CCKBR (0.61) | CCKBRCCKAR | |
| SCHEMBL4996686 | 0.66 | CCKBR (0.61) | CCKBRCCKAR | |
| SCHEMBL4992176 | 0.65 | CYP1A2 (0.59) | CCKBRCCKARALDH1A1THRB | |
| SCHEMBL8606321 | 0.63 | ALDH1A1 (0.43) | CCKBRCCKARALDH1A1POLBTHRB | |
| SCHEMBL3910889 | 0.63 | CCKBR (0.69) | CCKBRCCKAR | |
| SCHEMBL23352254 | 0.61 | CYP1A2 (0.45) | CCKBRCCKARRIPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951466-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | Elan Pharmaceuticals, Inc. (US) | 1999-10-27 | — | — | EP | claimed |
| WO-1998028268-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS AS β-AMYLOID PEPTIDE RELEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 1998-07-02 | — | — | WO | claimed |