Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480071 | 0.74 | CCKBR (0.40) | ALDH1A1CCKBRPOLBTHRB | |
| SCHEMBL11750297 | 0.69 | MEN1 (0.35) | FDFT1ALDH1A1RXFP1TP53 | |
| SCHEMBL8016066 | 0.66 | KDM4E (0.43) | ALDH1A1CCKBRHTTSMN1; SMN2MAPT | |
| SCHEMBL11516311 | 0.65 | HTR2A (0.42) | ADRA2A | |
| SCHEMBL7069966 | 0.65 | TP53 (0.64) | ALDH1A1SMN1; SMN2MAPTOPRK1PDE4D | |
| SCHEMBL5222768 | 0.65 | OPRK1 (0.39) | CHRM2ADRA2AOPRK1PDE4D | |
| SCHEMBL8111542 | 0.63 | FDFT1 (0.56) | FDFT1 | |
| SCHEMBL5417682 | 0.63 | OPRK1 (0.65) | ALDH1A1CCKBRSMN1; SMN2MAPTCHRM2 | |
| SCHEMBL6961890 | 0.62 | FDFT1 (0.53) | FDFT1 | |
| SCHEMBL6961879 | 0.62 | FDFT1 (0.53) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1342719-A1 | Benzodiazepine derivatives useful as CCK-Receptor Antagonists | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2003-09-10 | — | — | EP | disclosed |