Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469768 | 0.93 | MAPT (0.41) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL7474864 | 0.83 | TMEM97 (0.39) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL7468971 | 0.80 | ITGB3 (0.42) | ALDH1A1MAPTITGB3ITGA2BITGAV | |
| Trifluoroacetic Acid SCHEMBL7481102 | 0.76 | ITGB3 (0.48) | ITGB3ITGA2BITGAV | |
| SCHEMBL7479149 | 0.74 | ITGB3 (0.40) | ALDH1A1ITGB3ITGA2BDRD2DRD3 | |
| SCHEMBL7481505 | 0.74 | DRD3 (0.41) | ALDH1A1LMNAMAPTSMN1; SMN2DRD2 | |
| Hydrochloric Acid SCHEMBL7472463 | 0.73 | DRD3 (0.42) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL7590360 | 0.73 | ITGB3 (0.41) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL7474275 | 0.73 | ITGB3 (0.51) | ALDH1A1MEN1KMT2ALMNAITGB3 | |
| SCHEMBL7407154 | 0.73 | ITGB3 (0.47) | ALDH1A1MEN1KMT2AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |