Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478252 | 0.85 | ITGB3 (0.47) | ITGB3ITGA2BITGAV | |
| SCHEMBL7474864 | 0.84 | TMEM97 (0.39) | NR1H2ESR2ALDH1A1MAPTATM | |
| SCHEMBL7419930 | 0.84 | NR1H2 (0.49) | NR1H2ESR2USP30ALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL7481102 | 0.81 | ITGB3 (0.48) | ITGB3ITGA2BITGAV | |
| SCHEMBL7480246 | 0.80 | ALDH1A1 (0.40) | ITGB3ITGA2BITGAVALDH1A1MAPT | |
| SCHEMBL7473247 | 0.78 | NR1H2 (0.47) | NR1H2ESR2USP30ALDH1A1MAPT | |
| SCHEMBL7481405 | 0.76 | NR1H2 (0.42) | ITGB3ITGA2BNR1H2ESR2ALDH1A1 | |
| SCHEMBL7465981 | 0.76 | NR1H2 (0.40) | ITGB3ITGA2BNR1H2ESR2ALDH1A1 | |
| SCHEMBL7468291 | 0.74 | NR1H2 (0.38) | NR1H2ESR2JAK2JAK3PTK2 | |
| Trifluoroacetic Acid SCHEMBL7480684 | 0.73 | ITGB3 (0.49) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777667-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | Dr. Karl Thomae GmbH (DE) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005194-A1 | CYCLIC BENZAZEPINE UREA DERIVATIVES WITH AGGREGATION-INHIBITING EFFECT | DR. KARL THOMAE GMBH (DE) | 1996-02-22 | — | — | WO | disclosed |