Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424750 | 0.87 | MMP1 (0.46) | MMP1CAPN1RENCTSLCTSK | |
| SCHEMBL8764285 | 0.82 | MMP1 (0.53) | MMP1MMECAPN1REN | |
| SCHEMBL7420777 | 0.81 | MMP1 (0.41) | MMP1CAPN1RENCTSLCTSK | |
| SCHEMBL8764249 | 0.81 | MMP1 (0.45) | MMP1MMECTSLCTSKCTSB | |
| SCHEMBL7426256 | 0.79 | MMP1 (0.54) | MMP1REN | |
| SCHEMBL7426614 | 0.79 | MMP1 (0.74) | MMP1MMEREN | |
| SCHEMBL6411607 | 0.79 | MMP1 (0.74) | MMP1MMEREN | |
| SCHEMBL7377811 | 0.79 | MMP1 (0.74) | MMP1MMEREN | |
| SCHEMBL7427886 | 0.76 | MMP1 (0.47) | MMP1MMECAPN1REN | |
| SCHEMBL8390276 | 0.75 | MME (0.68) | MMP1MMEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047450-A1 | ACE INHIBITOR-MMP INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999032150-A1 | ACE INHIBITOR-MMP INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |