Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010702 | 0.93 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7334833 | 0.90 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL8008767 | 0.87 | POLB (0.36) | ALDH1A1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL7480359 | 0.84 | NPC1 (0.38) | ALDH1A1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL7998651 | 0.83 | ALDH1A1 (0.34) | ALDH1A1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL7344697 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7476628 | 0.83 | POLB (0.35) | ALDH1A1KDM4EMEN1KMT2ATP53 | |
| SCHEMBL7342170 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7335732 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7966903 | 0.81 | MAPT (0.36) | ALDH1A1KDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |