Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FABP1 | P07148 | 1/20 | 0.34 |
| ▸ | FABP6 | P51161 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919980 | 0.82 | ALDH1A1 (0.49) | ALDH1A1GAATSHRTP53KMT2A | |
| SCHEMBL8104964 | 0.82 | ALDH1A1 (0.49) | ALDH1A1GAATSHRTP53KMT2A | |
| SCHEMBL9229478 | 0.72 | ALDH1A1 (0.39) | ALDH1A1GAAKMT2AMEN1HDAC6 | |
| SCHEMBL4237258 | 0.71 | ALDH1A1 (0.56) | ALDH1A1GAATSHRTP53KMT2A | |
| SCHEMBL20214572 | 0.69 | ALDH1A1 (0.57) | ALDH1A1GAATSHRTP53KMT2A | |
| SCHEMBL7481341 | 0.69 | CNR1 (0.55) | ALDH1A1GAATSHRTP53KMT2A | |
| SCHEMBL20214571 | 0.69 | ALDH1A1 (0.57) | ALDH1A1GAATSHRTP53KMT2A | |
| SCHEMBL7486579 | 0.66 | CNR1 (0.59) | ALDH1A1GAATSHRTP53KMT2A | |
| SCHEMBL7479714 | 0.65 | CYP1A2 (0.53) | ALDH1A1GAAKMT2AMEN1GFER | |
| SCHEMBL571502 | 0.62 | ALDH1A1 (0.64) | ALDH1A1GAATSHRTP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551048-B1 | 2-imidazoline-5-one and 2-imidazoline-5-thiones derivatives as fungizides | AVENTIS CROPSCIENCE SA (FR) | 2002-08-07 | — | — | EP | disclosed |
| US-6344564-B1 | FUNGICIDES | RHONE-POULENC, INC. | 2002-02-05 | — | — | US | disclosed |
| US-6018052-A | APPLYING TO CROPS OR THEIR SEEDS TO PREVENT OR CURE FUNGAL DISEASES; STEREOSPECIFIC COMPOUND WITH IMPROVED BIOLOGICAL ACTIVITY | RHONE-POULENC AGROCHIMIE (FR) | 2000-01-25 | — | — | US | disclosed |
| US-6008370-A | FUNGICIDAL IMIDAZOLINONE AND IMIDAZOLINETHIONE COMPOUNDS FOR USE IN PLANT PROTECTION | RHONE-POULENC AGROCHIMIE (FR) | 1999-12-28 | — | — | US | disclosed |
| US-6002016-A | Fungicidal 2-imidazolin-5-ones and 2-imidazoline-5-thiones | RHONE-POULENC AGROCHIMIE (FR) | 1999-12-14 | — | — | US | disclosed |
| CN-1035594-C | Derivatives of 2-imidazoline-5-ketone and 2-imidazoline-5-thioketone for killing funguses | RHONE POULENC AGROCHIMIE (FR) | 1997-08-13 | — | — | CN | disclosed |
| US-5650519-A | Optically active 5, 5-disubstituted-3-(mono- or disubstituted amino)-2-thiohydantoin intermediates to fungicidal 2-imidazolin-5-ones | RHONE-POULENC AGROCHIMIE (FR) | 1997-07-22 | — | — | US | disclosed |
| US-5637729-A | AGRICULTURE | RHONE-POULENC AGROCHIMIE (FR) | 1997-06-10 | — | — | US | disclosed |
| EP-0551048-A1 | 2-imidazoline-5-one and 2-imidazoline-5-thiones derivatives as fungizides | RHONE-POULENC AGROCHIMIE (FR) | 1993-07-14 | — | — | EP | disclosed |