Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12601424 | 0.75 | ALDH1A1 (0.62) | ALDH1A1GAATSHRTP53LMNA | |
| SCHEMBL3387075 | 0.75 | ALDH1A1 (0.60) | ALDH1A1GAATSHRTP53LMNA | |
| SCHEMBL1919973 | 0.75 | KMT2A (0.60) | ALDH1A1GAATSHRTP53LMNA | |
| SCHEMBL13045977 | 0.75 | ALDH1A1 (0.60) | ALDH1A1GAATSHRTP53LMNA | |
| SCHEMBL20214572 | 0.73 | ALDH1A1 (0.57) | ALDH1A1GAATSHRTP53LMNA | |
| SCHEMBL20214571 | 0.73 | ALDH1A1 (0.57) | ALDH1A1GAATSHRTP53LMNA | |
| SCHEMBL4237258 | 0.71 | ALDH1A1 (0.56) | ALDH1A1GAATSHRTP53LMNA | |
| SCHEMBL17622984 | 0.71 | KMT2A (0.73) | ALDH1A1GAAKMT2AMEN1HTT | |
| SCHEMBL8282180 | 0.71 | ALDH1A1 (0.58) | ALDH1A1GAATSHRTP53LMNA | |
| SCHEMBL10246027 | 0.70 | ALDH1A1 (0.57) | ALDH1A1GAATSHRTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550622-B2 | Cycloalkylamidoacid compounds, processes for making and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-23 | — | — | US | claimed |
| US-11192875-B2 | Processes for preparing antiviral compounds | GILEAD PHARMASSET LLC (US) | 2021-12-07 | — | — | US | disclosed |
| US-20200392100-A1 | PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2020-12-17 | — | — | US | disclosed |
| US-10584109-B2 | Processes for preparing antiviral compounds | Gillead Pharmasset LLC (US) | 2020-03-10 | — | — | US | disclosed |
| US-20190263771-A1 | PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2019-08-29 | — | — | US | disclosed |
| US-20180179175-A1 | PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC | 2018-06-28 | — | — | US | disclosed |
| US-9890134-B2 | Processes for preparing antiviral compounds | GILEAD PHARMASSET LLC (US) | 2018-02-13 | — | — | US | disclosed |
| US-20170283390-A1 | PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2017-10-05 | — | — | US | disclosed |
| US-9670187-B2 | Processes for preparing antiviral compounds | GILEAD PHARMASSET LLC (US) | 2017-06-06 | — | — | US | disclosed |
| EP-3154984-A1 | PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2017-04-19 | — | — | EP | disclosed |
| WO-2015191437-A1 | PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2015-12-17 | — | — | WO | disclosed |
| US-20150361073-A1 | PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2015-12-17 | — | — | US | disclosed |
| US-20130274284-A1 | PREPARATION OF PRASUGREL HYDROCHLORIDE | DR. REDDY'S LABORATORIES, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| EP-2601200-A2 | PREPARATION OF PRASUGREL HYDROCHLORIDE | Dr. Reddy's Laboratories Ltd. (IN) | 2013-06-12 | — | — | EP | disclosed |
| EP-1656340-B1 | Processes for making 1-carbamoylcycloalkylcarboxylic acid compounds | BOEHRINGER INGELHEIM INT (DE) | 2012-07-18 | — | — | EP | disclosed |
| WO-2012018791-A2 | PREPARATION OF PRASUGREL HYDROCHLORIDE | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-02-09 | — | — | WO | disclosed |
| US-7550622-B2 | Cycloalkylamidoacid compounds, processes for making and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-23 | — | — | US | disclosed |
| EP-1656340-A1 | 1-CARBAMOYLCYCLOALKYLCARBOXYLIC ACID COMPOUNDS, PROCESSES FOR MAKING AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2006-05-17 | — | — | EP | disclosed |
| US-20050085544-A1 | Cycloalkylamidoacid compounds, processes for making and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-04-21 | — | — | US | disclosed |
| WO-2005019158-A1 | 1-CARBAMOYLCYCLOALKYLCARBOXYLIC ACID COMPOUNDS, PROCESSES FRO MAKING AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10584109-B2 | Processes for preparing antiviral compounds | MAVS, EIF2AK2, SAMHD1 | ALDH1A1 3004/4885GAA 150/4885TSHR 4459/4885 |
| US-11192875-B2 | Processes for preparing antiviral compounds | MAVS, EIF2AK2, SAMHD1 | ALDH1A1 3004/4885GAA 150/4885TSHR 4459/4885 |
| US-20170283390-A1 | PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, SAMHD1 | ALDH1A1 3004/4885GAA 150/4885TSHR 4459/4885 |
| US-20130274284-A1 | PREPARATION OF PRASUGREL HYDROCHLORIDE | PFKP, PF4, PTAFR | ALDH1A1 1209/4885GAA 1530/4885TSHR 3661/4885 |
| US-20150361073-A1 | PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, SAMHD1 | ALDH1A1 3004/4885GAA 150/4885TSHR 4459/4885 |
| US-20180179175-A1 | PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, SAMHD1 | ALDH1A1 3004/4885GAA 150/4885TSHR 4459/4885 |
| US-20200392100-A1 | PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, SAMHD1 | ALDH1A1 3004/4885GAA 150/4885TSHR 4459/4885 |
| US-20050085544-A1 | Cycloalkylamidoacid compounds, processes for making and uses thereof | ACMSD, QPCT, DCXR | ALDH1A1 757/4885GAA 103/4885TSHR 3727/4885 |
| US-20190263771-A1 | PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, SAMHD1 | ALDH1A1 3004/4885GAA 150/4885TSHR 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.