Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27536525 | 0.95 | DNM1 (0.49) | DNM1NPC1HPGDRAB9AMEN1 | |
| SCHEMBL7474984 | 0.88 | DNM1 (0.50) | DNM1MAPTDGKA | |
| SCHEMBL7479855 | 0.88 | NPC1 (0.44) | NPC1HPGDRAB9AMEN1TP53 | |
| SCHEMBL7474618 | 0.87 | MEN1 (0.45) | NPC1HPGDRAB9AMEN1TP53 | |
| SCHEMBL8180891 | 0.86 | MEN1 (0.45) | DNM1NPC1HPGDRAB9AMEN1 | |
| SCHEMBL7470070 | 0.86 | MEN1 (0.45) | DNM1NPC1HPGDRAB9AMEN1 | |
| SCHEMBL7475264 | 0.86 | DNM1 (0.44) | DNM1DGKA | |
| SCHEMBL7483673 | 0.86 | MEN1 (0.43) | NPC1HPGDRAB9AMEN1TP53 | |
| SCHEMBL8168628 | 0.86 | MEN1 (0.45) | DNM1NPC1HPGDRAB9AMEN1 | |
| SCHEMBL7479926 | 0.86 | MEN1 (0.45) | DNM1NPC1HPGDRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |