Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 3/20 | 0.31 |
| ▸ | CES1 | P23141 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830144 | 0.78 | GRM8 (0.32) | GRM8GRM6GRM4MEN1KMT2A | |
| SCHEMBL7471164 | 0.76 | GRM8 (0.39) | GRM8GRM6GRM4CES2CES1 | |
| SCHEMBL6389061 | 0.72 | EPHX1 (0.35) | GRM8GRM6GRM4 | |
| SCHEMBL7464198 | 0.72 | CES2 (0.62) | CES2CES1 | |
| SCHEMBL7469784 | 0.70 | LMNA (0.32) | — | |
| SCHEMBL7080150 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL8615396 | 0.64 | GRM8 (0.32) | GRM8GRM6GRM4 | |
| SCHEMBL407601 | 0.64 | — | — | |
| SCHEMBL7563688 | 0.64 | — | — | |
| SCHEMBL19735013 | 0.64 | HDAC3 (0.45) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |