Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470913 | 0.91 | HTT (0.41) | HSD17B10HTTHPGDKDM4EALDH1A1 | |
| SCHEMBL7473148 | 0.84 | MAPK14 (0.44) | ALDH1A1MAPTLMNATSHRNPC1 | |
| SCHEMBL7480550 | 0.84 | KDM4E (0.35) | HSD17B10HTTHPGDKDM4EALDH1A1 | |
| SCHEMBL7468981 | 0.83 | CYP11B1 (0.41) | HSD17B10HTTHPGDALDH1A1LTC4S | |
| SCHEMBL7474779 | 0.82 | ALDH1A1 (0.45) | HTTALDH1A1SRD5A2MAPTLMNA | |
| SCHEMBL7479307 | 0.81 | GLA (0.39) | HPGDKDM4EALDH1A1GLALTC4S | |
| SCHEMBL7475152 | 0.81 | MAPK14 (0.44) | HSD17B10HTTHPGDKDM4EALDH1A1 | |
| SCHEMBL7470675 | 0.81 | HTT (0.41) | HSD17B10HTTHPGDALDH1A1GLA | |
| SCHEMBL7471841 | 0.77 | MAPK14 (0.44) | HTTALDH1A1MAPTLMNANPC1 | |
| SCHEMBL7476225 | 0.76 | CYP11B1 (0.41) | HSD17B10HTTMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |