Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430313 | 0.85 | EPHX2 (0.49) | ALDH1A1ALDH2ALDH3A1MEN1KMT2A | |
| SCHEMBL7480896 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL7683513 | 0.72 | HTT (0.42) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL4985909 | 0.69 | GAA (0.49) | ALDH1A1ALDH2ALDH3A1PARK7MEN1 | |
| SCHEMBL31202677 | 0.68 | CYP1A2 (0.40) | ACHEALDH1A1MEN1KMT2AGAA | |
| SCHEMBL4283301 | 0.66 | KMT2A (0.56) | ACHEDAOMEN1KMT2AL3MBTL1 | |
| SCHEMBL4997317 | 0.64 | ALDH1A1 (0.48) | ALDH1A1ALDH2ALDH3A1PARK7MEN1 | |
| SCHEMBL31161862 | 0.64 | ACHE (0.55) | ACHEALDH1A1DAOMEN1KMT2A | |
| SCHEMBL10335076 | 0.64 | DDB1 (0.51) | ACHEALDH1A1DAOMEN1KMT2A | |
| SCHEMBL2132367 | 0.64 | L3MBTL1 (0.60) | ACHEMEN1KMT2AL3MBTL1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951466-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | Elan Pharmaceuticals, Inc. (US) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998028268-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS AS β-AMYLOID PEPTIDE RELEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 1998-07-02 | — | — | WO | disclosed |