Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.50 |
| ▸ | CFD | P00746 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | F11 | P03951 | 1/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5098921 | 0.99 | MRGPRX4 (0.52) | MRGPRX4MAOBPTGER1PTGDR2PTGER4 | |
| SCHEMBL5098912 | 0.90 | MRGPRX4 (0.54) | MRGPRX4MAOBPTGER1PTGDR2FFAR4 | |
| SCHEMBL6332053 | 0.87 | MRGPRX4 (0.52) | MRGPRX4MAOBPTGER1PTGDR2PPIA | |
| SCHEMBL17764541 | 0.85 | CFD (0.70) | MRGPRX4PTGER1PTGDR2PTGER4PTGER3 | |
| SCHEMBL6554874 | 0.85 | MAOB (0.55) | MRGPRX4MAOBPTGER1PTGDR2PPIA | |
| SCHEMBL1978691 | 0.85 | MAOB (0.55) | MRGPRX4MAOBPTGER1PTGDR2PPIA | |
| SCHEMBL8676493 | 0.82 | MAOB (0.55) | MRGPRX4MAOBPTGER1PTGDR2PPIA | |
| SCHEMBL8409660 | 0.82 | HTR1A (0.59) | MRGPRX4MAOBPTGER1FFAR4FFAR1 | |
| SCHEMBL6212565 | 0.82 | MAOB (0.55) | MRGPRX4MAOBPTGER1PPIA | |
| SCHEMBL7369714 | 0.81 | LTA4H (0.51) | MRGPRX4MAOBPTGER1PTGDR2PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425641-B2 | Carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2008-09-16 | — | — | US | disclosed |
| US-20050065346-A1 | Carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-03-24 | — | — | US | disclosed |
| US-6838565-B2 | Substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-01-04 | — | — | US | disclosed |
| US-20040138309-A1 | Novel substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM (DE) | 2004-07-15 | — | — | US | disclosed |
| EP-1206446-B1 | CARBOXYLIC ACID AMIDES, THEIR PRODUCTION AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-05-26 | — | — | EP | disclosed |
| US-20040077729-A1 | New carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-04-22 | — | — | US | disclosed |
| WO-2004013128-A1 | NOVEL SUBSTITUTED BENZAMIDES PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM (DE) | 2004-02-12 | — | — | WO | disclosed |
| EP-1370540-A1 | ANTI-THROMBOTIC CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2003-12-17 | — | — | EP | disclosed |
| EP-1360170-A1 | CARBOXYLIC AMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2003-11-12 | — | — | EP | disclosed |
| US-20020183519-A1 | Antithrombotic carboxylic acid amides | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-12-05 | — | — | US | disclosed |
| US-20020151595-A1 | Carboxylic acid amides having antithrombotic activity | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-10-17 | — | — | US | disclosed |
| WO-2002072558-A1 | ANTI-THROMBOTIC CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-09-19 | — | — | WO | disclosed |
| WO-2002062748-A1 | CARBOXYLIC AMIDES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138309-A1 | Novel substituted benzoic acid amides, their preparation and their use as pharmaceutical compositions | F11, F12, SERPINC1 | MRGPRX4 2604/4885MAOB 445/4885PTGER1 86/4885 |
| US-20020183519-A1 | Antithrombotic carboxylic acid amides | SERPINC1, TFPI, F2 | MRGPRX4 2438/4885MAOB 743/4885PTGER1 299/4885 |
| US-20040077729-A1 | New carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | F2, F11, F12 | MRGPRX4 2054/4885MAOB 417/4885PTGER1 226/4885 |
| US-20050065346-A1 | Carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | F12, F11, F2 | MRGPRX4 1925/4885MAOB 164/4885PTGER1 218/4885 |
| US-20020151595-A1 | Carboxylic acid amides having antithrombotic activity | SERPINC1, TFPI, F2 | MRGPRX4 3149/4885MAOB 1337/4885PTGER1 217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.