Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14359600 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AESR1POLB | |
| SCHEMBL4514477 | 0.82 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AESR1POLB | |
| SCHEMBL7479037 | 0.78 | MEN1 (0.47) | ALDH1A1MEN1KMT2AESR1POLB | |
| SCHEMBL7481753 | 0.78 | PTGS1 (0.52) | ALDH1A1MEN1KMT2AESR1POLB | |
| SCHEMBL7482405 | 0.78 | PTGS1 (0.52) | ALDH1A1MEN1KMT2AESR1POLB | |
| SCHEMBL7483292 | 0.78 | HTT (0.51) | ALDH1A1MEN1KMT2AESR1POLB | |
| SCHEMBL7480871 | 0.78 | HTT (0.51) | ALDH1A1MEN1KMT2AESR1POLB | |
| SCHEMBL7490240 | 0.78 | PTGS1 (0.52) | ALDH1A1MEN1KMT2AESR1POLB | |
| SCHEMBL7487859 | 0.77 | SMN1; SMN2 (0.50) | ALDH1A1MEN1KMT2AESR1POLB | |
| SCHEMBL2768849 | 0.77 | HTT (0.59) | ALDH1A1MEN1KMT2AESR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929522-B1 | INSECT-REPELLENT FORMULATIONS | PFIZER LTD (GB) | 2002-12-18 | — | — | EP | disclosed |
| US-6130241-A | Insect-repellent formulations | PFIZER INC. (US) | 2000-10-10 | — | — | US | disclosed |