Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475226 | 0.84 | NFKB1 (0.48) | LIPESRD5A2NPC1RAB9ADRD2 | |
| SCHEMBL16825145 | 0.81 | GRM5 (0.47) | MAPTSRD5A2KDM1AMAOASMN1; SMN2 | |
| SCHEMBL25935482 | 0.76 | LIPE (0.40) | LIPEMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL30969048 | 0.72 | LIPE (0.38) | LIPEALDH1A1DRD2KMT2AL3MBTL1 | |
| SCHEMBL7480298 | 0.71 | GPR119 (0.45) | MAPTSMN1; SMN2DRD2KMT2ACTSS | |
| SCHEMBL26266001 | 0.71 | LIPE (0.42) | LIPEALDH1A1KMT2AL3MBTL1CTSK | |
| SCHEMBL31309729 | 0.68 | LIPE (0.58) | LIPEDRD2 | |
| SCHEMBL23119314 | 0.68 | GRM5 (0.50) | — | |
| SCHEMBL10627455 | 0.68 | LIPE (0.45) | LIPEDRD2 | |
| SCHEMBL28817595 | 0.68 | RECQL (0.41) | LIPEALDH1A1CYP1A2CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227090-A1 | AMINE DERIVATIVES | Tadeka Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |