Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13082451 | 0.77 | PDCD1 (0.36) | — | |
| SCHEMBL7480952 | 0.73 | CDK1 (0.30) | — | |
| SCHEMBL7477808 | 0.72 | — | — | |
| SCHEMBL251411 | 0.69 | MAPKAPK2 (0.36) | — | |
| SCHEMBL3839050 | 0.66 | CRHR1 (0.33) | — | |
| SCHEMBL1426102 | 0.66 | NOS3 (0.33) | — | |
| SCHEMBL24215029 | 0.65 | APOBEC3A (0.36) | — | |
| Hydrochloric Acid SCHEMBL28003422 | 0.63 | NOS3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL28003421 | 0.63 | NOS3 (0.31) | — | |
| SCHEMBL6350199 | 0.63 | TP53 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255740-A2 | SUBSTITUTED ARYLPYRAZINES | NEUROGEN CORPORATION (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001060806-A2 | SUBSTITUTED ARYLPYRAZINES | NEUROGEN CORPORATION (US) | 2001-08-23 | — | — | WO | disclosed |