SCHEMBL7482199

SCHEMBL7482199

CC(c1nc2cc(F)c(F)cc2[nH]1)c1nc2ccc(C(=O)NC(CP(=O)(O)O)C(=O)O)cc2n1C

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 4/20 0.38
ACSS2 Q9NR19 7/20 0.38
TYMS P04818 2/20 0.37
PLG P00747 2/20 0.36
TPSAB1 Q15661 2/20 0.35
TPSD1 Q9BZJ3 2/20 0.35
TPSG1 Q9NRR2 2/20 0.35
IKBKB O14920 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7490565 0.91 PIN1 (0.41) PIN1ACSS2TYMSPLGTPSAB1
SCHEMBL7479311 0.89 ACSS2 (0.37) PIN1ACSS2TYMSPLGTPSAB1
SCHEMBL7478946 0.89 ACSS2 (0.39) PIN1ACSS2IKBKB
SCHEMBL7421962 0.89 PIN1 (0.35) PIN1ACSS2IKBKB
SCHEMBL7489855 0.89 PIN1 (0.46) PIN1ACSS2IKBKB
SCHEMBL7482513 0.88 PIN1 (0.41) PIN1ACSS2
SCHEMBL7481103 0.88 PIN1 (0.35) PIN1ACSS2PLGTPSAB1TPSD1
Hydrochloric Acid SCHEMBL7478353 0.88 PIN1 (0.45) PIN1ACSS2IKBKB
SCHEMBL7486158 0.87 ACSS2 (0.38) PIN1ACSS2TYMSPLGTPSAB1
SCHEMBL7489355 0.87 PIN1 (0.34) PIN1ACSS2IKBKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000020400-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING HEPATITIS C INFECTIONS AXYS PHARMACEUTICALS, INC. (US) 2000-04-13 WO disclosed