Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7478353 | 0.99 | PIN1 (0.45) | PIN1L3MBTL1ALDH1A1FPR1KDM4E | |
| SCHEMBL7490792 | 0.92 | L3MBTL1 (0.47) | PIN1L3MBTL1ALDH1A1FPR1KDM4E | |
| SCHEMBL7421962 | 0.90 | PIN1 (0.35) | PIN1L3MBTL1ALDH1A1ACSS2IKBKB | |
| SCHEMBL7478946 | 0.90 | ACSS2 (0.39) | PIN1L3MBTL1ALDH1A1ACSS2AURKA | |
| SCHEMBL7482513 | 0.90 | PIN1 (0.41) | PIN1L3MBTL1KMT2ATDP1MEN1 | |
| SCHEMBL7490565 | 0.90 | PIN1 (0.41) | PIN1MAPTACSS2 | |
| SCHEMBL7482906 | 0.90 | IKBKB (0.37) | PIN1L3MBTL1KDM4EACSS2IKBKB | |
| SCHEMBL7481103 | 0.90 | PIN1 (0.35) | PIN1L3MBTL1ACSS2 | |
| SCHEMBL7482199 | 0.89 | PIN1 (0.38) | PIN1ACSS2IKBKB | |
| SCHEMBL7485173 | 0.88 | PIN1 (0.46) | PIN1L3MBTL1ALDH1A1FPR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000020400-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING HEPATITIS C INFECTIONS | AXYS PHARMACEUTICALS, INC. (US) | 2000-04-13 | — | — | WO | disclosed |