Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719492 | 0.85 | ALDH1A1 (0.48) | ALDH1A1ATMNAAATSHRHPGD | |
| Hydrochloric Acid SCHEMBL27896236 | 0.80 | SOAT1 (0.52) | ALDH1A1HPGDLMNACYP1A2SMN1; SMN2 | |
| SCHEMBL14463170 | 0.80 | ALDH1A1 (0.47) | ALDH1A1ATMNAAATSHRHPGD | |
| SCHEMBL5202981 | 0.79 | ALDH1A1 (0.45) | ALDH1A1ATMNAAATSHRHPGD | |
| Hydrochloric Acid SCHEMBL28099282 | 0.77 | SOAT1 (0.48) | ALDH1A1LMNACYP1A2SMN1; SMN2POLB | |
| SCHEMBL22954568 | 0.77 | ALDH1A1 (0.40) | ALDH1A1ATMNAAATSHRHPGD | |
| SCHEMBL40274 | 0.77 | ALDH1A1 (0.61) | ALDH1A1ATMNAAATSHRHPGD | |
| SCHEMBL24325993 | 0.76 | NAAA (0.47) | ALDH1A1NAAATSHRESR1LMNA | |
| SCHEMBL4313949 | 0.75 | ALDH1A1 (0.58) | ALDH1A1ATMNAAATSHRHPGD | |
| Formic Acid SCHEMBL28786714 | 0.75 | ALDH1A1 (0.46) | ALDH1A1ATMNAAATSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204654-A1 | BENZOFURYLPIPERAZINES AND BENZOFURYLHOMOPIPERAZINES: SEROTONIN AGONISTS | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009111-A1 | BENZOFURYLPIPERAZINES AND BENZOFURYLHOMOPIPERAZINES: SEROTONIN AGONISTS | ELI LILLY AND COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |