Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14463170 | 0.98 | ALDH1A1 (0.47) | ALDH1A1ATMTSHRHPGDMEN1 | |
| SCHEMBL4719492 | 0.92 | ALDH1A1 (0.48) | ALDH1A1ATMTSHRHPGDESR1 | |
| SCHEMBL17683993 | 0.91 | TSHR (0.39) | ALDH1A1TSHRMEN1KMT2AESR1 | |
| SCHEMBL24325993 | 0.89 | NAAA (0.47) | ALDH1A1TSHRESR1LMNAHCAR2 | |
| Formic Acid SCHEMBL28786714 | 0.88 | ALDH1A1 (0.46) | ALDH1A1ATMTSHRHPGDMEN1 | |
| SCHEMBL234860 | 0.83 | ALDH1A1 (0.47) | ALDH1A1ATMTSHRHPGDMEN1 | |
| SCHEMBL22954568 | 0.83 | ALDH1A1 (0.40) | ALDH1A1ATMTSHRHPGDESR1 | |
| SCHEMBL1812214 | 0.82 | ALOX15 (0.39) | ALDH1A1ATMTSHRMEN1KMT2A | |
| SCHEMBL1837607 | 0.82 | ALOX15 (0.39) | ALDH1A1ATMTSHRMEN1KMT2A | |
| SCHEMBL16391280 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ATMTSHRHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3009444-B1 | ALPHA-OXOACYL AMINO-CAPROLACTAM DERIVATIVE | SEIKAGAKU KOGYO CO LTD (JP) | 2017-12-20 | — | — | EP | disclosed |
| US-9636346-B2 | Alpha-oxoacyl amino-caprolactam derivative | SEIKAGAKU CORPORATION (JP) | 2017-05-02 | — | — | US | disclosed |
| US-9562042-B2 | α-oxoacyl amino-caprolactam | SEIKAGAKU CORPORATION (JP) | 2017-02-07 | — | — | US | disclosed |
| US-20160375031-A1 | ALPHA-OXOACYL AMINO-CAPROLACTAM DERIVATIVE | SEIKAGAKU KOGYO CO LTD (JP) | 2016-12-29 | — | — | US | disclosed |
| US-9481707-B2 | α-oxoacyl amino-caprolactam derivative | SEIKAGAKU CORPORATION (JP) | 2016-11-01 | — | — | US | disclosed |
| US-20160137691-A1 | ALPHA-OXOACYL AMINO-CAPROLACTAM DERIVATIVE | SEIKAGAKU CORPORATION (JP) | 2016-05-19 | — | — | US | disclosed |
| US-20160130266-A1 | ALPHA-OXOACYL AMINO-CAPROLACTAM BODY | SEIKAGAKU CORPORATION (JP) | 2016-05-12 | — | — | US | disclosed |
| EP-3009444-A1 | ALPHA-OXOACYL AMINO-CAPROLACTAM DERIVATIVE | Seikagaku Corporation (JP) | 2016-04-20 | — | — | EP | disclosed |
| EP-1758891-A2 | BENZIMIDAZOLONE CARBOXYLIC ACID DERIVATIVES | Pfizer Japan Inc. (JP) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123718-A2 | BENZIMIDAZOLONE CARBOXYLIC ACID DERIVATIVES | PFIZER JAPAN INC. (JP) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160375031-A1 | ALPHA-OXOACYL AMINO-CAPROLACTAM DERIVATIVE | OGFRL1, ARGLU1, COL1A1 | ALDH1A1 2538/4885ATM 4505/4885TSHR 2298/4885 |
| US-20160137691-A1 | ALPHA-OXOACYL AMINO-CAPROLACTAM DERIVATIVE | COL2A1, ARGLU1, COL1A1 | ALDH1A1 2481/4885ATM 4446/4885TSHR 2671/4885 |
| US-20160130266-A1 | ALPHA-OXOACYL AMINO-CAPROLACTAM BODY | ANPEP, COL2A1, PTMS | ALDH1A1 3563/4885ATM 4556/4885TSHR 3420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.