Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.69 |
| ▸ | MAOB | P27338 | 5/20 | 0.63 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | AGXT | P21549 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anisole SCHEMBL11636165 | 0.93 | LOXL2 (0.64) | LTA4HMAOBLOXL2TAAR1SIGMAR1 | |
| Ethylbenzene SCHEMBL15227867 | 0.92 | LTA4H (0.60) | LTA4HMAOBLOXL2TAAR1SIGMAR1 | |
| SCHEMBL8755 | 0.91 | MAOB (0.73) | LTA4HMAOBTAAR1SLC6A4ALDH1A1 | |
| SCHEMBL4951818 | 0.91 | MAOB (0.73) | LTA4HMAOBTAAR1SLC6A4ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL9173570 | 0.89 | MAOB (0.70) | LTA4HMAOBTAAR1SLC6A4ALDH1A1 | |
| Bromide SCHEMBL31513712 | 0.89 | MAOB (0.70) | LTA4HMAOBTAAR1SLC6A4ALDH1A1 | |
| Iodide SCHEMBL28780684 | 0.89 | MAOB (0.70) | LTA4HMAOBTAAR1SLC6A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1715149 | 0.89 | MAOB (0.77) | LTA4HMAOBTAAR1SLC6A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7011298 | 0.86 | MAOB (0.68) | LTA4HMAOBTAAR1SLC6A4ALDH1A1 | |
| Bicarbonate SCHEMBL25353301 | 0.85 | MAOB (0.61) | LTA4HMAOBLOXL2TAAR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259489-A1 | ARYL FUSED AZAPOLYCYCLIC COMPOUNDS | Pfizer Products Inc. (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001062736-A1 | ARYL FUSED AZAPOLYCYCLIC COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2001-08-30 | — | — | WO | disclosed |