Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671177 | 0.87 | HTT (0.58) | ALDH1A1KDM4ETDP1HTTKMT2A | |
| SCHEMBL7332137 | 0.77 | KMT2A (0.52) | ALDH1A1KDM4EHTTKMT2ASMN1; SMN2 | |
| SCHEMBL12768059 | 0.74 | SLC6A3 (0.63) | ALDH1A1KDM4EHTTKMT2AMAPT | |
| SCHEMBL13390691 | 0.74 | SMN1; SMN2 (0.61) | ALDH1A1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL28408420 | 0.74 | KCNB1 (0.60) | ALDH1A1TDP1HTTSMN1; SMN2 | |
| SCHEMBL7411536 | 0.74 | TDP1 (0.69) | ALDH1A1KDM4ETDP1KMT2ASMN1; SMN2 | |
| SCHEMBL16300543 | 0.72 | KDM4E (0.47) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL5755555 | 0.72 | GRM4 (0.55) | ALDH1A1KDM4EKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL26886587 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4EHTTKMT2ASMN1; SMN2 | |
| SCHEMBL26886517 | 0.71 | MTNR1B (0.47) | ALDH1A1KDM4EKMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865281-B1 | NAPHTHYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTICOAGULANTS | BERLEX LAB (US) | 2002-04-03 | — | — | EP | disclosed |
| US-5849759-A | Naphthyl-substituted benzimidazole derivatives as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1998-12-15 | — | — | US | disclosed |