Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.50 |
| ▸ | CTSG | P08311 | 2/20 | 0.44 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665337 | 0.77 | ALDH1A1 (0.47) | ELANELMNAKDM4EALDH1A1MAPT | |
| SCHEMBL7651737 | 0.73 | ALDH1A1 (0.35) | CYP2C19ALDH1A1MAPTBACE1BACE2 | |
| Fenamidone SCHEMBL550975 | 0.72 | CYP1A2 (0.38) | NPSR1LMNAALDH1A1MAPTBACE1 | |
| Fenamidone SCHEMBL15286728 | 0.72 | CYP1A2 (0.38) | NPSR1LMNAALDH1A1MAPTBACE1 | |
| Fenamidone SCHEMBL22306 | 0.72 | CYP1A2 (0.38) | NPSR1LMNAALDH1A1MAPTBACE1 | |
| SCHEMBL20719054 | 0.71 | TDP1 (0.39) | ELANEKDM4EALDH1A1BACE1 | |
| SCHEMBL7475363 | 0.71 | ALDH1A1 (0.33) | ALDH1A1MAPTBACE1BACE2 | |
| Fenamidone SCHEMBL17701153 | 0.71 | CYP1A2 (0.37) | NPSR1LMNAALDH1A1MAPTBACE1 | |
| SCHEMBL9231712 | 0.70 | CYP1A2 (0.32) | ELANECYP2C19NPSR1LMNAKDM4E | |
| Fenamidone SCHEMBL17701150 | 0.69 | CYP1A2 (0.35) | NPSR1LMNAALDH1A1MAPTBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551048-B1 | 2-imidazoline-5-one and 2-imidazoline-5-thiones derivatives as fungizides | AVENTIS CROPSCIENCE SA (FR) | 2002-08-07 | — | — | EP | disclosed |
| US-6344564-B1 | FUNGICIDES | RHONE-POULENC, INC. | 2002-02-05 | — | — | US | disclosed |
| US-6018052-A | APPLYING TO CROPS OR THEIR SEEDS TO PREVENT OR CURE FUNGAL DISEASES; STEREOSPECIFIC COMPOUND WITH IMPROVED BIOLOGICAL ACTIVITY | RHONE-POULENC AGROCHIMIE (FR) | 2000-01-25 | — | — | US | disclosed |
| US-6008370-A | FUNGICIDAL IMIDAZOLINONE AND IMIDAZOLINETHIONE COMPOUNDS FOR USE IN PLANT PROTECTION | RHONE-POULENC AGROCHIMIE (FR) | 1999-12-28 | — | — | US | disclosed |
| US-6002016-A | Fungicidal 2-imidazolin-5-ones and 2-imidazoline-5-thiones | RHONE-POULENC AGROCHIMIE (FR) | 1999-12-14 | — | — | US | disclosed |
| US-5650519-A | Optically active 5, 5-disubstituted-3-(mono- or disubstituted amino)-2-thiohydantoin intermediates to fungicidal 2-imidazolin-5-ones | RHONE-POULENC AGROCHIMIE (FR) | 1997-07-22 | — | — | US | disclosed |
| US-5637729-A | AGRICULTURE | RHONE-POULENC AGROCHIMIE (FR) | 1997-06-10 | — | — | US | disclosed |
| EP-0551048-A1 | 2-imidazoline-5-one and 2-imidazoline-5-thiones derivatives as fungizides | RHONE-POULENC AGROCHIMIE (FR) | 1993-07-14 | — | — | EP | disclosed |