Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | DHFR | P00374 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484402 | 0.77 | ELANE (0.50) | ALDH1A1LMNAELANEKDM4EMAPT | |
| SCHEMBL9234331 | 0.72 | SIRT1 (0.46) | MAPTMMP2MMP13PKM | |
| SCHEMBL7651737 | 0.70 | ALDH1A1 (0.35) | ALDH1A1MAPTBACE1BACE2 | |
| Fenamidone SCHEMBL550975 | 0.69 | CYP1A2 (0.38) | ALDH1A1LMNAMAPTBACE1BACE2 | |
| Fenamidone SCHEMBL15286728 | 0.69 | CYP1A2 (0.38) | ALDH1A1LMNAMAPTBACE1BACE2 | |
| Fenamidone SCHEMBL17701153 | 0.68 | CYP1A2 (0.37) | ALDH1A1LMNAMAPTBACE1BACE2 | |
| SCHEMBL7475363 | 0.68 | ALDH1A1 (0.33) | ALDH1A1MEN1MAPTKMT2ABACE1 | |
| SCHEMBL9231712 | 0.65 | CYP1A2 (0.32) | ALDH1A1LMNAELANEKDM4EMEN1 | |
| SCHEMBL9234360 | 0.65 | CYP1A2 (0.32) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL30942995 | 0.65 | ALDH1A1 (0.59) | ALDH1A1DHFRTSHRELANEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344564-B1 | FUNGICIDES | RHONE-POULENC, INC. | 2002-02-05 | — | — | US | disclosed |
| US-6018052-A | APPLYING TO CROPS OR THEIR SEEDS TO PREVENT OR CURE FUNGAL DISEASES; STEREOSPECIFIC COMPOUND WITH IMPROVED BIOLOGICAL ACTIVITY | RHONE-POULENC AGROCHIMIE (FR) | 2000-01-25 | — | — | US | disclosed |
| US-6002016-A | Fungicidal 2-imidazolin-5-ones and 2-imidazoline-5-thiones | RHONE-POULENC AGROCHIMIE (FR) | 1999-12-14 | — | — | US | disclosed |
| US-5650519-A | Optically active 5, 5-disubstituted-3-(mono- or disubstituted amino)-2-thiohydantoin intermediates to fungicidal 2-imidazolin-5-ones | RHONE-POULENC AGROCHIMIE (FR) | 1997-07-22 | — | — | US | disclosed |
| US-5637729-A | AGRICULTURE | RHONE-POULENC AGROCHIMIE (FR) | 1997-06-10 | — | — | US | disclosed |
| EP-0551048-A1 | 2-imidazoline-5-one and 2-imidazoline-5-thiones derivatives as fungizides | RHONE-POULENC AGROCHIMIE (FR) | 1993-07-14 | — | — | EP | disclosed |