Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | BACE1 | P56817 | 6/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenamidone SCHEMBL15286728 | 0.73 | CYP1A2 (0.38) | ALDH1A1BACE1BACE2RENAPP | |
| Fenamidone SCHEMBL550975 | 0.73 | CYP1A2 (0.38) | ALDH1A1BACE1BACE2RENAPP | |
| Fenamidone SCHEMBL22306 | 0.73 | CYP1A2 (0.38) | ALDH1A1BACE1BACE2RENAPP | |
| SCHEMBL7484402 | 0.73 | ELANE (0.50) | ALDH1A1BACE1BACE2MAPTCYP2C19 | |
| Fenamidone SCHEMBL17701153 | 0.72 | CYP1A2 (0.37) | ALDH1A1BACE1BACE2RENAPP | |
| SCHEMBL7475363 | 0.72 | ALDH1A1 (0.33) | ALDH1A1BACE1BACE2RENAPP | |
| Fenamidone SCHEMBL27841614 | 0.72 | CYP1A2 (0.37) | ALDH1A1BACE1BACE2RENAPP | |
| SCHEMBL9251032 | 0.70 | CYP1A2 (0.33) | ALDH1A1GAAMAPTCYP2C19 | |
| SCHEMBL9234316 | 0.70 | CYP1A2 (0.33) | ALDH1A1GAAMAPTCYP2C19 | |
| SCHEMBL7665337 | 0.70 | ALDH1A1 (0.47) | ALDH1A1BACE1BACE2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344564-B1 | FUNGICIDES | RHONE-POULENC, INC. | 2002-02-05 | — | — | US | disclosed |
| US-6018052-A | APPLYING TO CROPS OR THEIR SEEDS TO PREVENT OR CURE FUNGAL DISEASES; STEREOSPECIFIC COMPOUND WITH IMPROVED BIOLOGICAL ACTIVITY | RHONE-POULENC AGROCHIMIE (FR) | 2000-01-25 | — | — | US | disclosed |
| US-6008370-A | FUNGICIDAL IMIDAZOLINONE AND IMIDAZOLINETHIONE COMPOUNDS FOR USE IN PLANT PROTECTION | RHONE-POULENC AGROCHIMIE (FR) | 1999-12-28 | — | — | US | disclosed |
| US-6002016-A | Fungicidal 2-imidazolin-5-ones and 2-imidazoline-5-thiones | RHONE-POULENC AGROCHIMIE (FR) | 1999-12-14 | — | — | US | disclosed |
| US-5650519-A | Optically active 5, 5-disubstituted-3-(mono- or disubstituted amino)-2-thiohydantoin intermediates to fungicidal 2-imidazolin-5-ones | RHONE-POULENC AGROCHIMIE (FR) | 1997-07-22 | — | — | US | disclosed |
| US-5637729-A | AGRICULTURE | RHONE-POULENC AGROCHIMIE (FR) | 1997-06-10 | — | — | US | disclosed |