Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.52 |
| ▸ | CCR8 | P51685 | 1/20 | 0.51 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625352 | 0.86 | KDM4E (0.73) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL7489376 | 0.86 | MEN1 (0.63) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL17912917 | 0.86 | KDM4E (0.65) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL7618274 | 0.85 | ALDH1A1 (0.72) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL1627052 | 0.85 | MEN1 (0.77) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL30072188 | 0.82 | KMT2A (0.55) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL26024357 | 0.82 | KMT2A (0.56) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL1904635 | 0.81 | MEN1 (0.71) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL1188654 | 0.81 | MEN1 (0.71) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL4937902 | 0.81 | MEN1 (0.71) | MEN1KMT2APOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1095839-C | 4,5-diaryl oxazole derivatives | FUJISAWA PHARMACETICAL CO LTD (JP) | 2002-12-11 | — | — | CN | disclosed |
| EP-0842161-B1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-09-18 | — | — | EP | disclosed |
| EP-1213285-A2 | 4,5-dipheny-oxazole derivatives and their use as platelet aggregation inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6300344-B1 | FOR THERAPEUTIC AND/OR PROPHYLACTIC TREATMENT OF ARTERIAL OBSTRUCTION, CEREBROVASCULAR DISEASE, HEPATIC CIRRHOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASE, RESTENOSIS AFTER PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY, HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| US-5972965-A | USEFUL FOR INHIBITION OF PLATELET AGGREGATION, VASODILATION, ANTIHYPERTENSIVE ACTIVITY AND PROSTAGLANDIN AGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| CN-1196726-A | 4,5-diaryl oxazole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-10-21 | — | — | CN | disclosed |
| EP-0842161-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997003973-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-06 | — | — | WO | disclosed |